Laboratory Design Guidelines Facilities Services-Books Pdf

Laboratory Design Guidelines Facilities Services
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Department of Facilities Services, Laboratory Design Guidelines. 2 Scope 22, 3 Storage of Compressed Gas Cylinders General Location 22. 4 Storage of Compressed Gas Cylinders Toxic and Highly Toxic Gases 23. 5 Storage of Compressed Gas Cylinders Medical Gases 24. VI FLAMMABLE LIQUID STORAGE CABINETS 25, 1 Codes Standards and References 25. 2 Scope 25, 3 Design 25, 4 Construction 26, VII HAZARDOUS MATERIALS STORAGE AND HANDLING 27. 1 Standards 27, 2 Scope 27, 3 Requirements 27, 4 Procedures 28.
VIII ADDITIONAL REQUIREMENTS FOR LABORATORIES USING RADIOACTIVE MATERIALS. RADIATION PRODUCING MACHINES OR LASERS 29, 1 Codes Standards and References 29. 2 Scope 30, 3 Decommissioning of Existing Facilities Prior to Demolition or Renovation 30. 4 Design Features for Radiological Labs 30, 5 Ventilation Considerations 31. 5 Laser Radiation Items 32, 5 Laser Ventilation Considerations 32. IX BIOSAFETY LEVEL 2 LABORATORIES 32, 1 Codes Standards and References 32.
2 Scope 33, 3 Ventilation Considerations for Biosafety Level 2 Laboratories 33. 4 Biological Safety Cabinets and Other Containment Considerations 33. X GLOSSARY 35, 2013 Design Guidelines 2 P a g e, Department of Facilities Services. Laboratory Design Guidelines, I INTRODUCTION, Purpose UNC Chapel Hill has a continuing need to modernize and upgrade its facilities The resulting. construction projects often have significant health and safety requirements due to regulatory oversight Since. these requirements can impact the design of a project the Department of Environment Health and Safety EHS. prepared this EHS Laboratory Design Guide to aid the campus community with planning and design issues. EHS believes that the Guide in conjunction with EHS s plan review and consultation improves design. efficiency and minimizes changes The main number for the UNC EHS Office is 919 962 5507. Application The Guide is a resource document for use by faculty staff and design professionals for use. during the planning and early design phases of a project The Guide applies to construction projects for all. UNC Chapel Hill facilities including leased properties. Format of Guide The Guide is formatted to address laboratory design issues pertinent to General Laboratories. e g chemical laboratories in Section II through VII with additional requirements for Radioactive Materials. Laboratories and Biosafety Level 2 Laboratories presented in Sections VIII and IX respectively Within the. sections specific design criteria are provided, References Please note that if any Design Guidelines are less stringent than the current NC Building Code. Mechanical Code Fire Prevention Code etc it should be brought to the attention of the EHS Department for. discussion and revision as necessary The Design Guidelines are not intended to preempt NC Code without. State approval of Alternate Methods and Materials where these Guidelines are found to be less stringent. Design criteria are designated in the following ways. Shall Criterion is typically mandated by applicable regulation s The user of the Guide is required to. include the design feature, Must Criterion is based on well established consensus standards guidelines Must is used to reflect a.
UNC requirement although not required by a regulation The use. the design feature, Should Criterion is advisory in nature based on good engineering and safety practices It is the discretion. of the user of the Guide to include the design feature. Limitations of the Guide The EHS Laboratory Design Guide is not all inclusive It does not cover all. regulatory issues nor does it cover all design situations It is important to note that use practices must be. considered during the design process as they can directly influence how the laboratory will be designed e g. how hazardous materials are used impacts how they are stored which is a design issue In all cases EHS should. be consulted on questions regarding health safety and the environment. II GENERAL REQUIREMENTS FOR UNC CHAPEL HILL, LABORATORIES. 1 Codes Standards and References, i Regulations, 1 Federal Code of Regulations CFR Title 29 Labor. 2 NC Building Code, 3 NC Fire Prevention Code, 4 NC Mechanical Code. 2013 Design Guidelines 3 P a g e, Department of Facilities Services.
Laboratory Design Guidelines, 5 CDC Select Agents Title 42 Part 73. 6 National Fire Protection Association NFPA Handbook 70. 7 National Electric Code, 8 NC Radiation Control Regulations. ii Consensus Standards and References, 1 American National Standard for Laboratory Ventilation ANSI AIHA Z9 5. 2 American National Standard for Thermal Environmental Conditions for Human Occupancy. ANSI ASHRAE 55 1992, 3 NC Radiation Protection Section. 4 Safe Handling of Radioactive Materials National Council on Radiation Protection NBS. 92 Handbook, 5 Safe Handling of Radionuclides International Atomic Energy Agency Safety Series No 1.
1973 ed is still current as of 1999 IAEA, 6 CDC NIH Biosafety in Microbiological and Biomedical Laboratories 5th or latest Edition. 7 Guidelines for Research Involving Recombinant DNA Molecules NIH Guidelines April. 2002 or latest, 8 Reducing the Risks of Nonstructural Earthquake Damage A Practical Guide Federal. Emergency Management Agency FEMA 74 1994, The primary objective in laboratory design is to provide a safe environment for laboratory personnel. to conduct their work Therefore all health and safety hazards must be identified and carefully. evaluated so that protective measures can be incorporated into the design The basic laboratory. design features listed in this section illustrate some of the basic health and safety elements to include. in all new and remodeled laboratories at UNC The subsections of Section 2 1 provide specific. guidance on additional critical features of a general laboratory e g fume hoods hazardous. materials storage and compressed gases Keep in mind however that no matter how well designed. a laboratory is improper usage of its facilities will always defeat the engineered safety features. 3 Architectural Considerations, i Walls Doors Security. The laboratory must be completely separated from outside areas i e must be bound by four. The laboratory shall have means of securing specifically regulated materials such as DEA. Controlled Substances CDC Select Agents and radioactive materials i e lockable doors. lockable cabinets etc, Having secured hazardous materials storage will keep unauthorized personnel from gaining.
access to them These regulations apply specifically to laboratories containing radioactive. materials CDC Select Agents and DEA Controlled Substances however UNC Chapel Hill EHS. interprets this to include all laboratories e g general chemistry and electronics. Laboratories which may use CDC Select Agents shall have secured entry doors that upon illegal. entry alarm to DPS and EHS, 2013 Design Guidelines 4 P a g e. Department of Facilities Services, Laboratory Design Guidelines. Doors in H occupancy laboratories shall have doors which swing in the direction of egress. Doors serving B occupancy shall swing in the direction of egress if the occupant load is 50 or. more Where possible all B occupancy lab doors should swing out with hardware satisfying. ADA requirements, On the next to each door entry into the laboratory an 8 5 x 11 inch space must be provided for a. standardized clear frame with the room number and hazard warning sheet insert landscape. orientation, Each door into a laboratory room must have a view panel. Inside the laboratory on the wall adjacent to the door latch provide 2 feet of clear space for light. switches telephone thermostat and fire extinguisher. Vents are prohibited in laboratory doors which open to egress access corridors. Laboratories which use hoods or other larger equipment should be equipped with doorways that. have 48 inch openings Each opening should accommodate a 36 active door leaf and a 12 inch. inactive leaf, iii Windows, If the laboratory has windows that open they must be fitted with insect screens.
iv Flooring, The floor must be a one piece non pervious and with covings to the wall This can be achieved by. use of glue heat welded vinyl flooring epoxy coated concrete slab etc. Floors should be coved up walls and cabinets to ensure spills cannot penetrate underneath. floors cabinets Tiles and wooden planks are not appropriate because liquids can seep through the. small gaps between them These references apply specifically to laboratories containing. biological and radioactive materials however UNC Chapel Hill EHS interprets this to include. all laboratories e g general chemistry electronics etc. Floors in storage areas for corrosive liquids shall be of liquid tight construction. Each laboratory must contain a sink for hand washing Elbow or electronic sensing faucet. controls are recommended particularly for biological agents and or highly toxic chemicals. Sink faucets and hose bibs that are intended for use with attached hoses must be equipped with. back siphon prevention devices, Laboratory sinks shall have lips that protect sink drains from spills. Sink lips or berms should be 0 25 inches and designed to completely separate the lab bench or. fume hood work area from the sink drain, 2013 Design Guidelines 5 P a g e. Department of Facilities Services, Laboratory Design Guidelines. vi Chemical Waste Storage, Chemical storage shelves shall not be placed above laboratory sinks.
Chemical storage shelves shall be flush to a back wall and shall have a inch lip along the front. Sufficient space or facilities e g storage cabinets with partitions shall be provided so that. incompatible chemicals can be physically separated This will be based on the chemical. inventory and use projection provided by the Principal Investigator to the project and EHS If the. project scope cannot provide sufficient storage the user must develop a written management. control plan to include as part of their local Chemical Hygiene Plan. Materials which in combination with other substances may cause a fire or explosion or may. liberate a flammable or poisonous gas must be kept separate Recommend that solvent storage. not be located under the laboratory fume hood as this is a location where fires are most likely to. occur in laboratories, Adequate space must be provided for the collection of waste materials. All labs should be designed to conveniently and safely accommodate the temporary storage of. biological radiological and chemical wastes based on laboratory use projections Wastes are. generally stored in the lab in which they are generated not in centralized accumulation areas. Contact EHS if waste storage and space become design challenges. vii Furniture Design and Location Exit Paths, All furniture must be sturdy All work surfaces e g bench tops and counters must be. impervious to the chemicals used, For example many microbiological manipulations involve concurrent use of chemical solvents. such as formaldehyde phenol and ethanol as well as corrosives The lab bench must be resistant. to the chemical actions of these substances and disinfectants Wooden bench tops are not. appropriate because an unfinished wood surface can absorb liquids Also wood burns rapidly in. the event of a fire Fiberglass is inappropriate since it can degrade when strong disinfectants are. applied Fiberglass also releases toxic smoke when burned These references apply specifically to. laboratories containing biological and radioactive materials however UNC Chapel Hill EHS. interprets this to include all laboratories e g general chemistry and electronics. The lab shall have a minimum aisle clearance of at least 24 inches Main aisles used for. emergency egress must have a clearance width of at least 36 inches. Lab benches and other furniture must be placed a minimum of 36 inches from an exit. Lab desks should be located near exit ways and in the path of fresh make up air. viii Cleanability, The laboratory must be designed so that it can be easily cleaned Walls should be painted with. washable hard non porous paints, Spaces between benches cabinets and equipment must be accessible for cleaning.
2013 Design Guidelines 6 P a g e, Department of Facilities Services. Laboratory Design Guidelines, Laboratory furniture must have smooth non porous surfaces so as to resist the absorption of. liquids and the harsh effects of disinfectants Furniture must not be positioned in such a manner. that makes it difficult to clean spilled liquids or conduct routine maintenance These references. apply specifically to laboratories containing biological and radioactive materials however UNC. Chapel Hill EHS interprets this to include all laboratories e g general chemistry and. electronics, ix Breakrooms, The design of the laboratory building must incorporate adequate additional facilities for food. storage consumption and personal hygiene tasks outside of the rooms where chemical and. biological materials are handled, Break rooms should be sized based upon floor occupancy and must be dedicated as a break area. and not serve other functions such as a copy center or equipment storage. A minimum of 1 break room is required per floor unless separate desk space is provided for each. occupant in office areas which are walled off and separately ventilated from the laboratory space. x General Ventilation Considerations see also Section 2 2 for fume hood considerations. Laboratory Design Guidelines 2013 Design Guidelines 5 Page Doors in H occupancy laboratories shall have doors which swing in the direction of egress Doors serving B occupancy shall swing in the direction of egress if the occupant load is 50 or more Where possible all B occupancy lab doors should swing out with hardware satisfying

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